Publications

1. Danbolt, N C and Storm-Mathisen, J (1986) Inhibition by K+ of Na+-dependent D-aspartate uptake into brain membrane saccules. J Neurochem 47, 825-830.

2. Danbolt, N C and Storm-Mathisen, J (1986) Na+-dependent 'binding' of D-aspartate in brain membranes is largely due to uptake into membrane bounded saccules. J Neurochem 47, 819-824.

3. Danbolt, N.C. and Storm-Mathisen, J. (1986) Na+-dependent binding of D-aspartate: inhibition by K+. In: Excitatory Amino Acids, 473-475. Roberts, P J, Storm-Mathisen, J, and Bradford, H F. Macmillan.

4. Danbolt, N C, Pines, G, and Kanner, B I (1990) Purification and reconstitution of the sodium- and potassium-coupled glutamate transport glycoprotein from rat brain. Biochemistry US 29, 6734-6740.

5. Danbolt, N C, Storm-Mathisen, J, and Kanner, B I (1992) An [Na+ + K+]coupled L-glutamate transporter purified from rat brain is located in glial cell processes. Neuroscience 51, 295-310.

6. Hees, B, Danbolt, N C, Kanner, B I, Haase, W, Heitmann, K, and Koepsell, H (1992) A monoclonal antibody against a Na+-L-glutamate cotransporter from rat brain. J Biol Chem 267, 23275-23281.

7. Pines, G, Danbolt, N C, Bjørås, M, Zhang, Y, Bendahan, A, Eide, L, Koepsell, H, Storm-Mathisen, J, Seeberg, E, and Kanner, B I (1992) Cloning and expression of a rat brain L-glutamate transporter. Nature 360, 464-467.

8. Rauen, T, Jeserich, G, Danbolt, N C, and Kanner, B I (1992) Comparative analysis of sodium-dependent L-glutamate transport of synaptosomal and astroglial membrane vesicles from mouse cortex. FEBS Lett 312, 15-20.

9. Storm-Mathisen, J, Danbolt, N C, Rothe, F, Torp, R, Zhang, N, Aas, J E, Kanner, B I, Langmoen, I, and Ottersen, O P (1992) Ultrastructural immunocytochemical observations on the localization, metabolism and transport of glutamate in normal and ischemic brain tissue. Prog Brain Res 94, 225-241.

10. Casado, M, Bendahan, A, Zafra, F, Danbolt, N C, Aragón, C, Giménez, C, and Kanner, B I (1993) Phosphorylation and modulation of brain glutamate transporters by protein kinase C. J Biol Chem 268, 27313-27317.

11. Danbolt, C, Hansen, T W R, Øyasaeter, S, Storm-Mathisen, J, and Bratlid, D (1993) In vitro binding of [3H]bilirubin to neurons in rat brain sections. Biol Neonate 63, 35-39.

12. Danbolt, N.C., Ottersen, O.P., and Storm-Mathisen, J. (1993) Anatomy of glutamate: An amino acid studied by immunocytochemistry. In: Glutamate - Transmitter and Toxin, 12-29. Kempski, O. W. Zuckschwerdt Verlag: München, Bern, Wien, New York.

13. Gundersen, V , Danbolt, N C, Ottersen, O P, and Storm-Mathisen, J (1993) Demonstration of glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous D-aspartate. Neuroscience 57, 97-111.

14. Kanner, B I, Danbolt, N, Pines, G, Koepsell, H, Seeberg, E, and Mathisen, J S (1993) Structure and function of the sodium and potassium-coupled glutamate transporter from rat brain. Biochem Soc Trans 21, 59-61.

15. Levy, L M, Lehre, K P, Rolstad, B, and Danbolt, N C (1993) A monoclonal antibody raised against an [Na+ - K+]coupled L- glutamate transporter purified from rat brain confirms glial cell localization. FEBS Lett 317, 79-84.

16. Danbolt, N C (1994) The high affinity uptake system for excitatory amino acids in the brain. Prog Neurobiol 44, 377-396.

17. Danbolt, N C, Storm-Mathisen, J, and Ottersen, O P (1994) Sodium/potassium coupled glutamate transporters, a ''new'' family of eukaryotic proteins: do they have ''new'' physiological roles and could they be new targets for pharmacological intervention? Prog Brain Res 100, 53-60.

18. Torp, R, Danbolt, N C, Babaie, E, Bjørås, M, Seeberg, E, Storm-Mathisen, J, and Ottersen, O P (1994) Differential expression of two glial glutamate transporters in the rat brain: an in situ hybridization study. Eur J Neurosci 6, 936-942.

19. Chaudhry, F A, Lehre, K P, Campagne, M V, Ottersen, O P, Danbolt, N C, and Storm-Mathisen, J (1995) Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 15, 711-720.

20. Lehre, K P, Levy, L M, Ottersen, O P, Storm-Mathisen, J, and Danbolt, N C (1995) Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations. J Neurosci 15, 1835-1853.J Neurosci 15, 1835-1853.

21. Levy, L M, Lehre, K P, Walaas, S I, Storm-Mathisen, J, and Danbolt, N C (1995) Down-regulation of glial glutamate transporters after glutamatergic denervation in the rat brain. Eur J Neurosci 7, 2036-2041.

22. Torp, R, Lekieffre, D, Levy, L M, Haug, F M, Danbolt, N C, Meldrum, B S, and Ottersen, O P (1995) Reduced postischemic expression of a glial glutamate transporter, GLT1, in the rat hippocampus. Exp Brain Res 103, 51-58.

23. Trotti, D, Volterra, A, Lehre, K P, Rossi, D, Gjesdal, O, Racagni, G, and Danbolt, N C (1995) Arachidonic acid inhibits a purified and reconstituted glutamate transporter directly from the water phase and not via the phospholipid membrane. J Biol Chem 270 , 9890-9895.

24. Zafra, F, Aragón, C, Olivares, L, Danbolt, N C, Giménez, C, and Storm-Mathisen, J (1995) Glycine transporters are differentially expressed among CNS cells. J Neurosci 15, 3952-3969.

25. Bjørås, M, Gjesdal, O, Erickson, J D, Torp, R, Levy, L M, Ottersen, O P, Degree, M, Storm-Mathisen, J, Seeberg, E, and Danbolt, N C (1996) Cloning and expression of a neuronal rat brain glutamate transporter. Molecular Brain Research 36, 163-168.

26. Gegelashvili, G, Civenni, G, Racagni, G, Danbolt, N C, Schousboe, I, and Schousboe, A (1996) Glutamate receptor agonists up-regulate glutamate transporter GLAST in astrocytes. Neuroreport 8, 261-265.

27. Haugeto, Ø, Ullensvang, K, Levy, L M, Chaudhry, F A, Honoré, T, Nielsen, M, Lehre, K P, and Danbolt, N C (1996) Brain glutamate transporter proteins form homomultimers. J Biol Chem 271, 27715-27722.

28. Trotti, D, Rossi, D, Gjesdal, O, Levy, L M, Racagni, G, Danbolt, N C, and Volterra, A (1996) Peroxynitrite inhibits glutamate transporter subtypes. J Biol Chem 271, 5976-5979.

29. Trotti, D., Rossi, D., Rizzini, B.L., Bezzi, P., Danbolt, N.C., Racagni, G., and Volterra, A. (1996) Molecular mechanisms of functional alteration of glutamate transporters and relevance to neuropathology. In: Preclinical and Clinical Strategies for the Treatment of Neurodegenerative, Cerebrovascular and Mental Disorders, 41-48. Shibuya, T. Karger, CH-4009 Basel, Switzerland.

30. Volterra, A, Bezzi, P, Rizzini, B L, Trotti, D, Ullensvang, K, Danbolt, N C, and Racagni, G (1996) The competitive transport inhibitor L-trans-pyrrolidine-2,4- dicarboxylate triggers excitotoxicity in rat cortical neuron- astrocyte co-cultures via glutamate release rather than uptake inhibition. Eur J Neurosci 8, 2019-2028.

31. Akbar, M T, Torp, R, Danbolt, N C, Levy, L M, Meldrum, B S, and Ottersen, O P (1997) Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats. Neuroscience 78, 351-359.

32. Furness, D N and Lehre, K P (1997) Immunocytochemical localization of a high-affinity glutamate-aspartate transporter, GLAST, in the rat and guinea-pig cochlea. Eur J Neurosci 9, 1961-1969.

33. Gegelashvili, G, Danbolt, N C, and Schousboe, A (1997) Neuronal soluble factors differentially regulate the expression of the GLT1 and GLAST glutamate transporters in cultured astroglia. J Neurochem 69, 2612-2615.

34. Lehre, K P, Davanger, S, and Danbolt, N C (1997) Localization of the glutamate transporter protein GLAST in rat retina. Brain Res 744, 129-137.

35. Ottersen, O P, Chaudhry, F A, Danbolt, N C, Laake, J H , Nagelhus, E A, Storm-Mathisen, J, and Torp, R (1997) Molecular organization of cerebellar glutamate synapses. Prog Brain Res 114, 97-107.

36. Takumi, Y, Matsubara, A, Danbolt, N C, Laake, J H, Storm-Mathisen, J, Usami, S, Shinkawa, H, and Ottersen, O P (1997) Discrete cellular and subcellular localization of glutamine synthetase and the glutamate transporter GLAST in the rat vestibular end organ. Neuroscience 79, 1137-1144.

37. Torp, R, Hoover, F, Danbolt, N C, Storm-Mathisen, J, and Ottersen, O P (1997) Differential distribution of the glutamate transporters GLT1 and rEAAC1 in rat cerebral cortex and thalamus: an in situ hybridization analysis. Anat Embryol (Berl) 195, 317-326.

38. Trotti, D, Rizzini, B L, Rossi, D, Haugeto, Ø, Racagni, G, Danbolt, N C, and Volterra, A (1997) Neuronal and glial glutamate transporters possess an SH-based redox regulatory mechanism. Eur J Neurosci 9, 1236-1243.

39. Ullensvang, K, Lehre, K P, Storm-Mathisen, J, and Danbolt, N C (1997) Differential developmental expression of the two rat brain glutamate transporter proteins GLAST and GLT. Eur J Neurosci 9, 1646-1655.

40. Chaudhry, F A, Reimer, R J, Bellocchio, E E, Danbolt, N C, Osen, K K, Edwards, R H, and Storm-Mathisen, J (1998) The vesicular GABA transporter, VGAT, localizes to synaptic vesicles in sets of glycinergic as well as GABAergic neurons. J Neurosci 18, 9733-9750.

41. Danbolt, N C, Chaudhry, F A, Dehnes, Y, Lehre, K P, Levy, L M, Ullensvang, K, and Storm-Mathisen, J (1998) Properties and localization of glutamate transporters. Prog Brain Res 116, 23-43.

42. Danbolt, N C , Lehre, K P, Dehnes, Y, Chaudhry, F A, and Levy, L M (1998) Localization of transporters using transporter-specific antibodies. Methods Enzymol 296, 388-407.

43. Dehnes, Y, Chaudhry, F A, Ullensvang, K, Lehre, K P, Storm-Mathisen, J, and Danbolt, N C (1998) The glutamate transporter EAAT4 in rat cerebellar Purkinje cells: a glutamate-gated chloride channel concentrated near the synapse in parts of the dendritic membrane facing astroglia. J Neurosci 18, 3606-3619.

44. Lehre, K P and Danbolt, N C (1998) The number of glutamate transporter subtype molecules at glutamatergic synapses: chemical and stereological quantification in young adult rat brain. J Neurosci 18, 8751-8757.

45. Levy, L M, Attwell, D, Hoover, F, Ash, J F, Bjørås, M, and Danbolt, N C (1998) Inducible expression of the GLT-1 glutamate transporter in a CHO cell line selected for low endogenous glutamate uptake. FEBS Lett 422, 339-342.

46. Levy, L M, Warr, O, and Attwell, D (1998) Stoichiometry of the glial glutamate transporter GLT-1 expressed inducibly in a chinese hamster ovary cell line selected for low endogenous Na+-dependent glutamate uptake. J Neurosci 18, 9620-9628.

47. Mennerick, S , Dhond, R P, Benz, A, Xu, W Y, Rothstein, J D, Danbolt, N C, Isenberg, K E, and Zorumski, C F (1998) Neuronal expression of the glutamate transporter GLT-1 in hippocampal microcultures. J Neurosci 18, 4490-4499.

48. Trotti, D, Danbolt, N C, and Volterra, A (1998) Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol Sci 19, 328-334.

49. Weber, J R, Ørstavik, S, Torgersen, K M, Danbolt, N C, Berg, S F, Ryan, J C, Tasken, K, Imboden, J B, and Vaage, J T (1998) Molecular cloning of the cDNA encoding pp36, a tyrosine- phosphorylated adaptor protein selectively expressed by T cells and natural killer cells. J Exp Med 187, 1157-1161.

50. Beckstrøm, H, Julsrud, L, Haugeto, Ø, Dewar, D, Graham, D I, Lehre, K P, Storm-Mathisen, J, and Danbolt, N C (1999) Interindividual differences in the levels of the glutamate transporters GLAST and GLT, but no clear correlation with Alzheimer's disease. J Neurosci Res 55, 218-229.

51. Mathern, G W , Mendoza, D, Lozada, A, Pretorius, J K, Dehnes, Y, Danbolt, N C, Nelson, N, Leite, J P, and Chimelli, L (1999) Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy. Neurology 52, 453-472.

52. Tessler, S, Danbolt, N C, Faull, R L M, Storm-Mathisen, J, and Emson, P C (1999) Expression of the glutamate transporters in human temporal lobe epilepsy. Neuroscience 88, 1083-1091.

53. Trotti, D, Rolfs, A, Danbolt, N C, Brown, R HJr, and Hediger, M A (1999) SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter. Nat Neurosci 2, 427-433.

54. Danbolt, N.C. (2000) Sodium- and potassium-dependent excitatory amino acid transporters in brain plasma membranes. In: Handbook of Chemical Neuroanatomy - Glutamate, 231-254. Ottersen, O P and Storm-Mathisen, J. Elsevier Science B. V.

55. Gegelashvili, G, Dehnes, Y, Danbolt, N C, and Schousboe, A (2000) The high-affinity glutamate transporters GLT1, GLAST and EAAT4 are regulated via different signalling mechanisms. Neurochem Int 37, 163-170.

56. Plachez, C, Danbolt, N C, and Recasens, M (2000) Transient expression of the glial glutamate transporters GLAST and GLT in hippocampal neurons in primary culture. J Neurosci Res 59, 587-593.

57. Danbolt, N C (2001) Glutamate uptake. Prog Neurobiol 65, 1-105.

58. Hazell, A S, Rao, K V, Danbolt, N C, Pow, D V, and Butterworth, R F (2001) Selective down-regulation of the astrocyte glutamate transporters GLT-1 and GLAST within the medial thalamus in experimental Wernicke's encephalopathy. J Neurochem 78, 560-568.

59. Trotti, D, Aoki, M, Pasinelli, P, Berger, U V, Danbolt, N C, Brown, R H Jr, and Hediger, M A (2001) Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity. J Biol Chem 276, 576-582.

60. Boulland, J L, Osen, K K, Levy, L M, Danbolt, N C, Edwards, R H, Storm-Mathisen, J, and Chaudhry, F A (2002) Cell-specific expression of the glutamine transporter SN1 suggests differences in dependence on the glutamine cycle. Eur J Neurosci 15, 1615-1631.

61. Danbolt, N.C., Lehre, K.P., Dehnes, Y., and Ullensvang, K. (2002) Transporters for synaptic transmitter on the glial cell plasma|membrane. In: The Tripartite Synapse - Glia in Synaptic Transmission, 47-61. Volterra, A, Magistretti, P J, and Haydon, P G. Oxford University Press: New York.

62. Gardiner, R B, Ullensvang, K, Danbolt, N C, Caveney, S , and Donly, B C (2002) Cellular distribution of a high-affinity glutamate transporter in the nervous system of the cabbage looper Trichoplusia ni. J Exp Biol 205, 2605-2613.

63. Lehre, K P and Rusakov, D A (2002) Asymmetry of glia near central synapses favors presynaptically directed glutamate escape. Biophys J 83, 125-134.

64. O'Shea, R D, Fodera, M V, Aprico, K, Dehnes, Y, Danbolt, N C, Crawford, D, and Beart, P M (2002) Evaluation of drugs acting at glutamate transporters in organotypic hippocampal cultures: New evidence on substrates and blockers in excitotoxicity. Neurochem Res 27, 5-13.

65. Rusakov, D A and Lehre, K P (2002) Perisynaptic asymmetry of glia: new insights into glutamatergic signalling. Trends Neurosci 25, 492-494.

66. Danbolt, N.C., Holmseth, S., Skår, A., Lehre, K.P., and Furness, D.N. (2004) Glutamate uptake and transporters. In: Excitotoxicity in Neurological Disease - New Therapeutic Challenge, 27-49. Ferrarese, C and Beal, M F. Kluwer Academic Publishers: Boston Dordrecht London.

67. Eid, T, Thomas, M J, Spencer, D D, Rundenpran, E, Lai, J C K, Malthankar, G V, Kim, J H, Danbolt, N C, Ottersen, O P, and Delanerolle, N C (2004) Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy. Lancet 363, 28-37.

68. Gammelsaeter, R, Frøyland, M, Aragon, C, Danbolt, N C, Fortin, D, Storm-Mathisen, J, Davanger, S, and Gundersen, V (2004) Glycine, GABA and their transporters in pancreatic islets of Langerhans: evidence for a paracrine transmitter interplay. J Cell Sci 117, 3749-3758.

69. Eid, T, Lee, T S, Thomas, M J, Amiry-Moghaddam, M, Bjørnsen, L P, Spencer, D D, Agre, P, Ottersen, O P, and de Lanerolle, N C (2005) Loss of perivascular aquaporin 4 may underlie deficient water and K+ homeostasis in the human epileptogenic hippocampus. Proc Natl Acad Sci U S A 102, 1193-1198.

70. Holmseth, S, Dehnes, Y, Bjørnsen, L P, Boulland, J L, Furness, D N, Bergles, D, and Danbolt, N C (2005) Specificity of antibodies unexpected cross reactivity of antibodies directed against the EAAT3 (EAAC) glutamate transporter. Neuroscience 136, 649-660.

71. Renden, R, Taschenberger, H, Puente, N, Rusakov, D A, Duvoisin, R, Wang, L Y, Lehre, K P, and von Gersdorff, H (2005) Glutamate transporter studies reveal the pruning of metabotropic glutamate receptors and absence of AMPA receptor desensitization at mature calyx of held synapses. J Neurosci 25, 8482-8497.

72. Rusakov, D A, Saitow, F, Lehre, K P, and Konishi, S (2005) Modulation of presynaptic Ca2+ entry by AMPA receptors at individual GABAergic synapses in the cerebellum. J Neurosci 25, 4930-4940.

73. Holmseth, S, Lehre, K P, and Danbolt, N C (2006) Specificity controls for immunocytochemistry. Anat Embryol (Berl) 211, 257-266.

74. Lee, T S, Bjørnsen, L P, Paz, C, Kim, J H, Spencer, S S, Spencer, D D, Eid, T, and Delanerolle, N C (2006) GAT1 and GAT3 expression are differently localized in the human epileptogenic hippocampus. Acta Neuropathol (Berl)111, 351-363.

75. O'Shea, R D, Lau, C L, Farso, M C, Diwakarla, S, Zagami, C J, Svendsen, B B, Feeney, S J, Callaway, J K, Jones, N M, Pow, D V, Danbolt, N C, Jarrott, B, and Beart, P M (2006) Effects of lipopolysaccharide on glial phenotype and activity of glutamate
transporters: Evidence for delayed up-regulation and redistribution of GLT-1. Neurochem Int 48, 604-610.

76. Bjørnsen, L P, Eid, T, Holmseth, S, Danbolt, N C, Spencer, D D, and de Lanerolle, N C (2007) Changes in glial glutamate transporters in human epileptogenic hippocampus: Inadequate explanation for high extracellular glutamate during seizures. Neurobiol Dis 25, 319-330.

77. Fontana, A C, de Oliveira Beleboni, R, Wojewodzic, M W, Ferreira Dos Santos, W, Coutinho-Netto, J, Grutle, N J, Watts, S D, Danbolt, N C, Amara, S G (2007) Enhancing glutamate transport: mechanism of action of Parawixin1, a neuroprotective compound from Parawixia bistriata spider venom. Mol Pharmacol 72, 1228-37.

78. Furness, D N, Dehnes, Y, Akhtar, A Q, Rossi, D J, Hamann, M, Grutle, N J, Gundersen, V, Holmseth, S, Lehre, K P, Ullensvang, K, Wojewodzic, M, Zhou, Y, Attwell, D, Danbolt, N C (2008) A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: New insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2). Neuroscience 157, 80-94

79. Holten, A T, Danbolt, N C, Shimamoto, K, Gundersen, V (2008) Low-affinity excitatory amino acid uptake in hippocampal astrocytes: a possible role of Na+/dicarboxylate cotransporters. Glia 56, 990-7.

80. Lehre, A, Lehre, K P, Laake, P, Danbolt, N C (2008) Greater intrasex phenotype variability in males than in females is a fundamental aspect of the gender differences in humans. Developmental Psychobiology 51, 198-206.

81. Lehre A, Hansen A, Laake P (2009) Gender and the 2003 Quality Reform in higher education. Higher Education 58, 585–597.

82. Holmseth S, Scott, H A, Real, K, Lehre, K P, Leergaard, T, Bjaalie, J G, Danbolt, N C (2009) The concentrations and distributions of three C-terminal variants of the GLT1 (EAAT2, slc1a2) glutamate transporter protein in rat brain tissue suggest differential regulation. Neuroscience 162, 1055-1071.

83. Mathiisen, T M, Lehre, K P, Danbolt, N C, Ottersen, O P (2010) The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction. Glia 58, 1094-1103.

84. Larsson, M, Morland, C, Poblete-Naredo, I, Biber, J, Danbolt, N C, Gundersen, V (2011) The sodium-dependent inorganic phosphate transporter SLC34A1 (NaPi-IIa) is not localized in the mouse brain: a case of tissue-specific antigenic cross-reactivity. J Histochem Cytochem 59:807-812.

85. Lehre, A C, Rowley, N M, Zhou, Y, Holmseth, S, Guo, C, Holen, T, Hua, R, Laake, P, Olofsson, A M, Poblete-Naredo, I, Rusakov, D A, Madsen, K K, Clausen, R P, Schousboe, A, White, H S, Danbolt, N C (2011) Deletion of the betaine-GABA transporter (BGT1,, slc6a12) gene does not affect seizure thresholds of adult mice. Epilepsy Res 95:70-81.

86. Ganzella, M, Moreira, J D, Almeida, R F, Bohmer, A E, Saute, J A, Holmseth, S, Souza, D O (2012) Effects of 3 weeks GMP oral administration on glutamatergic parameters in mice neocortex. Purinergic Signal 8:49-58.

87. Holmseth, S, Dehnes, Y, Huang, Y H, Follin-Arbelet, V V, Grutle, N J, Mylonakou, M N, Plachez, C, Zhou, Y, Furness, D N, Bergles, D E, Lehre, K P, Danbolt, N C (2012) The density of EAAC1 (EAAT3) glutamate transporters expressed by neurons in the mammalian CNS. J Neurosci 32:6000-6013.

88. Holmseth, S, Zhou, Y, Follin-Arbelet, V V, Lehre, K P, Bergles, D E, Danbolt, N C (2012) Specificity controls for immunocytochemistry: the antigen pre-adsorption test can lead to inaccurate assessment of antibody specificity. J Histochem Cytochem 60:174-187.

89. Li, Y, Zhou, Y, Danbolt, N C (2012) The rates of postmortem proteolysis of glutamate transporters differ dramatically between cells and between transporter subtypes. J Histochem Cytochem 60:811-821.

90. Zhou, Y, Holmseth, S, Guo, C, Hassel, B, Hofner, G, Huitfeldt, H S, Wanner, K T, Danbolt, N C (2012) Deletion of the gamma-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents. J Biol Chem 287:35733-35746.

91. Zhou, Y, Holmseth, S, Hua, R, Lehre, A C, Olofsson, A M, Poblete-Naredo, I, Kempson, S A, Danbolt, N C (2012) The betaine-GABA transporter (BGT1, slc6a12) is predominantly expressed in the liver and at lower levels in the kidneys and at the brain surface. Am J Physiol Renal Physiol 302:F316-328.

92. Zhou, Y, Danbolt, N C (2013) GABA and Glutamate Transporters in Brain. Front Endocrinol (Lausanne) 4:165.

93. Bjørnsen, L P, Hadera, M G, Zhou, Y, Danbolt, N C, Sonnewald, U (2014) The GLT-1 (EAAT2; slc1a2) glutamate transporter is essential for glutamate homeostasis in the neocortex of the mouse. J Neurochem.128:641-9.

94. Dehnes, Y, Shan, J, Beuming, T, Shi, L, Weinstein, H, Javitch, J A (2014) Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation. Neurochem Int. 73:4-15.

95. Kempson, S A, Zhou, Y, Danbolt, N C (2014) The betaine/GABA transporter and betaine: roles in brain, kidney, and liver. Front Physiol. 5:159.

96. Martinov, V, Dehnes, Y, Holmseth, S, Shimamoto, K, Danbolt, N C, Valen, G (2014) A novel glutamate transporter blocker, LL-TBOA, attenuates ischaemic injury in the isolated, perfused rat heart despite low transporter levels. Eur J Cardiothorac Surg. 45:710-6.

97. Zhou, Y, Danbolt, N C (2014) Glutamate as a neurotransmitter in the healthy brain. J Neural Transm. 121:799-817.

98. Zhou, Y, Waanders, L F, Holmseth, S, Guo, C, Berger, U V, Li, Y, Lehre, A C, Lehre, K P, Danbolt, N C (2014) Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice. J Biol Chem. 289:1329-44.

99. Zhou, Y, Wang, X Y, Tzingounis, A V, Danbolt, N C, Larsson, H P (2014) EAAT2 (GLT-1; slc1a2) glutamate transporters reconstituted in liposomes argues against heteroexchange being substantially faster than net uptake. J. Neurosci. In Press

100. Nordaas, M, Raynaud, X, Lehre, K P, Danbolt, N C (2015) Well-posedness of a diffusion model equation with reactive boundaries for neurotransmitters. Mathematical Models & Methods In Applied Sciences In press.