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The Neurotransporter Group - Research interests
The overall interest is the control of neurotransmitter concentrations and diffusion in the extracellular space in between synapses in the central nervous system
The group focus on the transporter proteins moving the transmitter amino
acids (GABA, glutamate and glycine) across cell membranes, and on the
roles of these transporter proteins in normal brain physiology and disease.
Perturbations in transporter function and expression have now been reported
in all neurological diseases, and these perturbations appear to be part
of the pathogenetic processes ultimately leading to nerve cell damage
and neurological and psychological disabilities (for review see: Danbolt,
2001).
Introduction to:
- Glutamate
- Neurotransporters
- Glutamate
uptake
- Cerebellum
On-going research activity